An innovative talk show that offers a multifaceted and revealing perspective on current affairs, highlighting the female angle with five participants from different generations, styles, nationalities, and cultures.

Desiguales is known for its diverse approach, with lively discussions on current topics, entertainment news, and personal stories from the hosts and their guests. With its relaxed and energetic style, the show has become a favorite of viewers seeking an entertaining and light experience. Additionally, it has been praised for its close connection with its audience, thanks to the blend of humor, personality, and current pop culture topics.