"Dottie the body" lost her confidence when a large bump started growing between her thighs. Dr. Lee brings in a new, young doctor to help Tim with his big, bumpy nose. Karime is insecure about her birthmark that looks like a black eye.

Tierra is a musician with massive bumps on her ears that hold her back from performing. Dr. Zoe assists Dr. Lee helping Ryan, whose numerous head bumps undermine his life journey. Ann keeps a great attitude even as she lives with everyday pain caused by her genetic skin condition.