Tana deals with an abusive past, and a forehead bump. Ernestine, a die-hard Yankees fan, has a huge, misshapen growth on her back. Dr. Lee teaches eager dermatology intern Dr. Hannah Tolson how to remove Foday's mystery bumps named Mama and Baby.

Veronica has a huge mango-sized growth on her back that has taken away her zest for life and desire for camping. Thomas has a deep passion for cosplay, but is too embarrassed to dress up due to the large, round bump on their head.