As she fights for a critically ill woman's heart transplant, Dr. Grace Devlin is asked by Constantine to kill her patient's estranged and imprisoned father in order to get the organ she needs to save her life.

When two innocent bystanders are caught up in an ambush meant for Franco and the rest of Moretti's crew, Grace joins the action. As the war between Moretti and Constantine escalates, Grace makes a critical move in an attempt to end the feud.