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As she fights for a critically ill woman's heart transplant, Dr. Grace Devlin is asked by Constantine to kill her patient's estranged and imprisoned father in order to get the organ she needs to save her life.
Dr. Grace Devlin must save the life of an old friend injured in a pub-crawl accident, while tasked by Constantine with delivering the child of a pregnant call girl. Meanwhile, Franco has to track down a young woman whose whereabouts are crucial to his boss.
Emotions reach a breaking point when Grace and Brett's relationship shows signs of strain due to their demanding and hectic schedules. Meanwhile, Grace finds herself in a perilous situation when mob boss Paul Moretti takes matters into his own hands.