John takes up bagpipes, then trombone, and finally guitar after Kelly jokes with him about playing the squad's horn. John and Roy treat a gardener suffering from tetanus, a driver of an ice cream truck trapped after a wreck, a girl who has overdosed on barbiturates, and later dies, and a pilot of a glider who crashed, and they also free a man trapped under his house. Dixie and Dr. Early talk to a couple whose son is suffering from lead poisoning, later found to be also suffering from deprivation dwarfism, and the father refuses to treat his son with experimental growth hormones.

John complains about drivers failing to yield to the squad when their lights are on, so he writes the Chief who employs a deputy to monitor driver behavior. A college quarterback suffers from muscle cramps affecting his back which sidelines him from a big weekend game, Roy and John teach a CPR class to a group of senior citizens, then learn that their former paramedic instructor has died from cardiac arrest. The firefighters rescue a boy stuck upside down in a tree, and assist people trapped in a large fire at a hotel, complicated by a cardiac victim on the third floor.