Lizzie races to Boston, where Emma has taken refuge in the luxurious home of Adele Trotwood and family, with whom she has a very special connection. Stunned to find a vastly different Emma than the cherished sister she knew, Lizzie unwittingly leads Bat Masterson and Tom Horn directly into their path. However, the Trotwood family proves to be more than your average Boston Brahmins, posing an unexpected challenge to Bat and Tom. Trying to ease tensions, Emma makes an impetuous sacrifice. Lizzie plumbs the depths of her cunning to set out to ambush the gunslingers, and somehow pull the sister she dearly loves back from the abyss.

Months after her showdown with Charles Siringo, Lizzie Borden has remade herself as a school teacher with a new name in a little town far from Fall River. Seeking peace in anonymity, she's here to be near her sister, Emma, whose reaction to ghastly events of the past has put her in an asylum, under the care of an egotistical but renowned doctor. Lizzie's unaware that two famed gunslingers, Bat Masterson and Tom Horn, are hunting her, driven to learn the fate of their friend, Siringo. When Lizzie helps a victimized student get justice Lizzie-style, she jeopardizes her cover. Worse, Emma makes a startling choice that leaves Lizzie devastated.

Pinkerton agent Charles Siringo and stage star Nance O'Keefe, who grows more desperate in her search for her missing brother, have been outplayed by Lizzie. But now they join forces against her. The sleazy new boss of Fall River's underworld, Skipjack, gleefully exploits a lethal secret Lizzie wants hidden. A haughty neighbor incites Lizzie's wrath by mistreating her dog. Worst of all, a romance threatens to come between Lizzie and her beloved her sister, Emma. When Nance uses her wiles to get Skipjack to spill his guts, her frenzied revenge against Lizzie spills blood... just not the blood Nance intended. Meantime, Lizzie mops up her animal-abusing neighbor with a spill of a different sort.

Pinkerton agent Charles Siringo and stage star Nance O'Keefe, who grows more desperate in her search for her missing brother, have been outplayed by Lizzie. But now they join forces against her. The sleazy new boss of Fall River's underworld, Skipjack, gleefully exploits a lethal secret Lizzie wants hidden. A haughty neighbor incites Lizzie's wrath by mistreating her dog. Worst of all, a romance threatens to come between Lizzie and her beloved her sister, Emma. When Nance uses her wiles to get Skipjack to spill his guts, her frenzied revenge against Lizzie spills blood... just not the blood Nance intended. Meantime, Lizzie mops up her animal-abusing neighbor with a spill of a different sort.

Pinkerton agent Charles Siringo and stage star Nance O'Keefe, who grows more desperate in her search for her missing brother, have been outplayed by Lizzie. But now they join forces against her. The sleazy new boss of Fall River's underworld, Skipjack, gleefully exploits a lethal secret Lizzie wants hidden. A haughty neighbor incites Lizzie's wrath by mistreating her dog. Worst of all, a romance threatens to come between Lizzie and her beloved her sister, Emma. When Nance uses her wiles to get Skipjack to spill his guts, her frenzied revenge against Lizzie spills blood... just not the blood Nance intended. Meantime, Lizzie mops up her animal-abusing neighbor with a spill of a different sort.

Lizzie plans a lavish housewarming party in her new mansion, when a beautiful New York actress shows up, distressed about her missing brother last seen with Lizzie. Local gangster Mr. Flowers twists the screws on Lizzie in an extortion scheme. Charles Siringo finally meets his anonymous employer, bent on finding the truth about Lizzie, and it doesn't go well. Both Mr. Flowers and Siringo discover too late that their manipulations backfire. Meanwhile, Lizzie's party is a surprising success, and, as a bonus, it infuriates her spiteful neighbors. The only problem is that pesky actress... Ever resourceful, Lizzie finds an opportunity to quash two threats at once.

Lizzie and sister Emma break out of their Victorian comfort zone at a debauched bohemian party in New York City. En route home, Lizzie saves a street prostitute from a vicious beating, then gives the scared young woman refuge in her own house. But her charity incurs the wrath of notorious local gangster, Mr. Flowers. A surprise visit by a dashing New York playwright is an amusing distraction as he plies his charm to convince Lizzie to finance his latest work. Pinkerton agent Siringo turns up fresh evidence that further incriminates Lizzie, while a sordid encounter between the hooker and the writer leads Lizzie to mediate the problem in her unique way.

After her shocking 1893 acquittal for the brutal axe-murders of her parents in Fall River, Massachusetts, Lizzie Borden, ignores the scorn of neighbors to restart her life with her loving older sister, Emma. But renowned Texas Pinkerton agent Charles Siringo shows up determined to find the real truth behind the murders. Their father's ex-business partner, William Almy demands payment of a colossal debt that will bankrupt the sisters. And their shiftless half-brother blackmails them with a dark secret. Lizzie is forced to reappraise the tranquil life she had in mind, and may have to resort to old bloody ways to escape this treacherous bind.