As the Thanksgiving holiday approaches, the Children of Liberty prepare a new initiative to wipe out the aliens among them. James and Lena have their first major argument, and Nia displays narcolepsy but refuses help.

Manchester learns Agent Liberty's secret identity and goes to obtain vengeance for Fiona's death. Nia has a prophetic dream, and Kara and Brainiac-5 help her to avoid the future that she has foreseen.