Neil deGrasse Tyson features his interview with former astronaut Mae Jemison and discusses the challenges of interstellar travel with comedian Godfrey and theoretical physicist Lawrence Krauss. Biomedical engineer Ronke Olabisi contributes.

Neil deGrasse Tyson interviews Stephen Colbert, host of "The Late Show" on CBS, and discusses the intersection of science and comedy with comedian Adam Conover and author Sophia McClennen. Father James Martin, SJ, joins them. Bill Nye, the Science Guy, also appears.