When a Louisiana man is shot in his sleep, detectives uncover details of his extracurricular love life and a death policy that promised to pay out, even in the event of his murder.

Sixteen-year-old Theresa Burns is brutally murdered in her family's Indiana home; though investigators believe they've found the murder weapon, it will take a quarter of a century before they close in on the killer.

The body of a 16-year-old high school cheerleader is found floating in a river bordering Texas and Oklahoma; the police investigation unearths several promising suspects, then a break points to a killer already in their midst.

After Genore Guillory is brutally murdered in her own home, investigators look at several suspects on the woman's final 24-hour timeline; unable to pin anyone down, the case goes cold, until a witness comes forward with the inside story.

A man comes home to find his fiancée dead in the bedroom of their new home; the discovery of infidelity soon puts him firmly in the hot seat; as investigators piece together the victim's final 24 hours, they uncover a sinister plot.

A double homicide in New York City soon becomes a media circus when investigators reveal the two victims led a secret life; as the list of suspects grows, it's a call from the victims' home that may provide the only link to the killer.

A successful vacuum salesman is gunned down outside his Indiana office; as detectives untangle the victims' final 24 hours, all the clues point to a hired hit.

When a woman is murdered in her Alabama home, investigators receive a lead pointing to a high-profile suspect, but it will take a decade before their circumstantial murder case has enough substance to go to trial.

In an affluent Atlanta suburb, a young boy is stabbed 18 times when he returns home from school, and his mother's lifeless body is discovered in her bedroom; a neighbor's chilling story points police toward a psychopath.

When Diane Holik's body is discovered in her Texas home, detectives are faced with one of the most pristine crime scenes they've ever encountered; they unearth multiple suspects, but only the victim's reconstructed timeline can identify the killer.

In rural Michigan, 34-year-old Deborah Boothby is run over on the highway, and for nine years the case goes unsolved. That is, until a team of detectives review the evidence and the hit-and-run cold case becomes a murder investigation.