The arrival of a traveling carnival in Cabot Cove coincides with a rash of burglaries and the murder of the troupe's owner.

Jessica searches for the truth when a legendary maestro is found murdered and an innocent man is charged with the crime.

While visiting a friend in Texas, Jessica attempts to help the owner of a small trucking company clear his son of a murder charge.

After arriving at Seth's office and discovering it in disarray and the good doctor nowhere to be found, Jessica and Sheriff Metzger fear the worst – especially after finding fresh bloodstains at various spots in the office. Their relief at finding Seth perfectly safe soon turns to befuddlement when a mysterious man turns up dead in the nearby woods. Upon investigating, they soon discover the man's connection to a local businessman's past in Boston, and that with the recent influx of newcomers to town; they have plenty of murder suspects.

Jessica has worked to have Larkins sold to a museum, but an embezzled pension plan leads to a rival bid and murder.

Jessica's teen writing class has two promising students, Alida and Chris. But when Chris' loan-shark stepfather turns up dead after pursuing Alida and fleeing a hit-and-run, Chris is the prime suspect.

In New York, Jessica's publisher Edward Graham seems to be cracking up following the death of his wife. But was a fall from the top of the building suicide or murder?

While planning a surprise birthday party for Seth, Jessica gets involved with a murder investigation when a hitman from Chicago appears to be killed by a local fisherman. Things then get trickier when it appears her friend Charlie Garrett is also somehow involved in the crime.

Jessica comes to the rescue when a friend's sculpture is used as a murder weapon.

While serving as the celebrity guest on a New York cooking show, hosted by renowned chef Bernardo Bonelli, Jessica gets drawn into an intriguing murder investigation when a new restaurant, when Bonelli is found dead on its opening night. While the police are certain that they have the murderer, Bonelli's assistant who invested a large amount of money in his restaurant and held an insurance policy on her investment, Jessica is certain that the young woman is being framed by a local mob boss. However, when the mob boss is then gunned down outside the restaurant, Jessica has to find out how both murders are connected.

While on a brief layover in a small Canadian mining town, Jessica finds herself pulled into an investigation when an explosion at a mine leaves an executive and an employee of the mining company dead and the prime suspect is a First Nations activist who was accused of stealing some dynamite the night before. Working with the Territory's Tribal lawyer and a RCMP cop, the trio set out to prove the young man's innocence.

When Jessica is called to London to rewrite the stage adaptation of her novel, she must prove her actress friend innocent of killing a producer.

One of Jessica's best-selling mysteries makes her the target of a lawsuit by a man who was tried and acquitted for murder.

Jessica returns to Cabot Cove to discover why her accountant is not paying her bills.

While visiting Ireland, Jessica searches for clues when a widowed friend's son is suspected of killing an American relative.

A racehorse trainer is murdered as he is on his way to expose a racing fraud.

Jessica happens on a computerized clue to a murder while writing a mystery story for a friend's interactive video game company.

Jessica comes to the aid of a promising young reporter when he is suspected of murdering a rival magazine's unscrupulous publisher.

While restoring her house in Cabot Cove, Jessica worries that her contractor is preoccupied by the remodeling of another house until the project is put on hold when the client is found murdered.

When Jessica agrees to help preserve a historic brownstone, she winds up trying to clear her editor of the murder of an opposing developer.

Jessica's trip to Hong Kong is interrupted by the murder of an American businessman negotiating a merger with a Chinese tycoon.

Production Notes: This season has the fourth opening segment, one that includes a desktop computer, and printer in the opening segment. Also they reshot the scene of her putting the pages in the binder. It now points towards the other direction.