When a physics professor at a major U.S. university steals weaponized uranium, the team scrambles to find the professor and the missing uranium before it can be used against an important international summit meeting in New York City.

The team is tasked with protecting a scientist who has developed a deadly technology that, in the wrong hands, could have devastating consequences to mankind. Meanwhile, Ryan and Shelby stumble on something personal of Alex's that signals a possible change in her personal life.