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Caitlyn, bent on proving her commitment to the LGBT cause, risks arrest in Houston with her friends; Ella tries to mend fences with her father, who struggles to accept her transition.
Cait's personal growth on the road trip is tested when she tries to apologize to her ex-wife, Kris, for her part in the ending of their marriage; Candis looks into her options to adopt a baby.
Kris visits Cait in New Orleans, to try improve their relationship, but when old wounds arise between the exes, Cait's friends must intervene.
When the newly sober Scott visits Cait on the road trip, they struggle to find common ground. Meanwhile, Cait and the women attend a ceremony for Transgender Day of Remembrance.
After Cait is challenged to show restraint during the Democratic debates, the women are challenged by a visit to Cait's alma mater, a conservative, Christian college in Iowa.
After witnessing Candis get stood up by a guy because she's trans, Cait reveals her deepest fears about dating men.
After a heated political argument on the bus, the women decide to confront Cait on her aggressive debating style and suggest a more feminine approach.
Cait and her friends embark on an epic cross-country road trip in a tour bus, and the other women take the opportunity to corner Cait about her sexual orientation and her politics.