Dr. Jeff takes on a high-risk surgery to save the life of an adored puppy. A three-day-old orphaned kitten needs Dr. Baier's help to stay alive. And, a pup is given a fifty-fifty chance of survival after it's rushed into the clinic with a deadly virus.

When a young Boxer falls from a 2nd story window, the team races to the rescue. Dr. Jeff discovers a life-threatening problem in a Great Dane. And, after a beloved cat is attacked by a mystery animal at night, Dr. Don battles to save his leg.