Mahfuza and Nelly are living with Harlequin ichthyosis, one of the world's rarest and most severe skin conditions; Mahfuza prepares for her first boxing match; Nelly fully supports her friend but worries that the high risks may outweigh the rewards.

Ecuadorian conjoined twins Jose Luis and Jose Armando leave their home and family to get advanced medical care for a chance at independence. Teenaged Thai conjoined twins Pin and Pan must navigate their ongoing differences they prepare for adulthood.