Most Extreme Humans follows people from around the globe living with the world's rarest and most remarkable physical conditions. From a Filipino man whose hands have grown so large he wears wristwatches as rings, to Brazil, where the world's smallest married couple have a combined height under six feet, to a 19-year-old in India living with the ultra-rare condition known as "werewolf syndrome." This series examines what everyday life looks like when the world is not built with your body in mind.