Hosted by legendary Greek singer Anna Vissi, Με Αγάπη Άννα was a weekly musical variety show. Combining live musical performances, celebrity interviews, comedy sketches and entertainment segments, the show offered audiences a different side of the popular singer.

The program featured appearances by various Greek artists, humorous sketches with actor Pavlos Haikalis, a karaoke competition with Michalis Tsousopoulos and a comedy segment titled Taxi, featuring Markos Seferlis in one of his earliest television appearances. Anna Vissi also performed throughout the show, bringing her distinctive musical style and stage presence to Greek television.