The annual year-end quiz, hosted by Jimmy Carr. Guests including Sarah Millican, James Acaster, Jonathan Ross and Judi Love look back on the strange events of 2021, from space travel and celebrities who do not shower, to sea shanties and Tony Blair's peculiar hair. Charles Dance and the children of Mitchell Brook Primary School are on hand to help Jimmy pose his questions.

Rob Beckett, Roisin Conaty, Nish Kumar, Katherine Ryan, Oti Mabuse and Rob Brydon join Jimmy Carr as he poses questions on anything and everything, with subjects including Only Fools and Horses, Johnny Cash and US tourist attractions. As always, Jimmy is helped by newsreader Jon Snow, actor Charles Dance and the children from Mitchell Brook Primary School.