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Owen and Amelia take their relationship to the next level; Alex gains some clarity on his future with Jo; and Callie and Arizona continue to struggle with the current custody arrangement.
Callie and Arizona are at odds over Sofia's future, and Stephanie questions the status of her relationship with Kyle. Meanwhile, Alex and April work on a pregnant teen that is readmitted to Grey Sloan Memorial.
Meredith and Maggie support Amelia on an important day; Jo reveals that she has been keeping secrets from Alex while Arizona and Callie deal with the impact of their custody arrangement. Meanwhile, Ben leaps into action to help a friend.
Meredith struggles to deal with all her responsibilities after Amelia moves in with her, while Miranda begins life as the new Chief of Surgery.