In Panama, police arrest two smugglers who claim local gangs stole their drugs, leading to a hunt for the thieves responsible. Also: U.S. Customs and Border Protection search for narcotics aboard a ferry in Puerto Rico.

Panamanian police get intel on a drug exchange. Units head out to surprise the traffickers, but the mission takes an unexpected turn. In Puerto Rico, U.S. Customs and Border Protection oversee the arrival of a ferry from the Dominican Republic.

Dominican authorities gather enough evidence to apprehend a cartel boss, but his possible getaway jeopardizes the arrest. Also: Volunteer work to save patients from drug addiction continues in Santo Domingo.

A Venezuelan cartel boss is tracked down in the Dominican Republic, after which law enforcement prepares to intercept one of his shipments. Elsewhere, a group of recovering addicts travel to the slums to help others struggling with dependency.

Local authorities in the Dominican Republic team up with U.S. law enforcement to investigate a cartel boss operating on the island.

The U.S Border Patrol receive intel about smugglers heading from the Dominican Republic to Puerto Rico. Several units deploy to the western side of the island only to find 11 migrants that have been abandoned on a remote island nearby.

U.S. Border Patrol works to protect Puerto Rico from drug smugglers; volunteers attempt to save the lives of drug addicts.

A drug stash is found in a deep cave system in Panama; Puerto Rican drug abuse increases.

Dominican authorities now have enough evidence to arrest the Cartel boss, but it looks like he might make a getaway before they have the chance. Volunteer work continues in Santo Domingo to save one patient at a time from drug addiction.

The US Coast Guard combats drug trafficking out of Colombia and Peru.