The Smith family gets ready to celebrate Roger's big 1-6-double-0 but are sidetracked by Steve's horrifying announcement that he's going through puberty! With the wounds still fresh from Hayley going through "the change" in their minds, Stan and Francine use experimental medicine to try and bypass the growing pains of having another teenager with raging hormones. Meanwhile, Roger gets the shaft from the family and tries to make his own birthday fun.

When Stan becomes his boss' go-to guy, he feels like he can't say no to anything including outrageous personal requests. But when Francine gets roped into the annoying ordeal and her romantic Valentine's Day get-away is ruined, she lays down the law and forces Stan to say "NO" .