Wayne's comment at a seminar offends some witches. The witches cast spells on the family. Now they must stop the witches and get Nick back.

Wayne invents an invention called the 3iDer which turns people into different people. The invention and Wayne got nominated for the inventors recognition achievement award. An evil clown tries to steal the invention and frame Wayne so it is up to Team Szalinski to stop this clown and clear Wayne's name.

While Wayne and Diane are out celebrating the anniversary of their first date, Amy's party is crashed by a group of aliens contacted by Nick using one of Wayne's communication gizmos. One of the aliens, through his bizzare home world customs, marries Amy after using a device to make the family some-what subserviant to her. Finding out their true origins, Amy demands her family be turned back to normal and their "marriage" be ended. Both are undone and he aliens part ways on good terms.

Wayne is knocked senseless by a tree while trudging home in a blizzard and awakens to find himself on trial in Dreamland because of his erratic inventions.

A new boss has taken over Jentech west and there is a new guy. Wayne's uncle finds out some info about this guy after Wayne told him to leave him alone and not interfere. This turns out to be important info because the guy who became Wayne's new supervisor steals inventions and patents them as his own.

Amy's science teacher quits unexpectedly so her dad volunteers to teach. He makes a formula to make him charming so that the students will like him. Amy catches him and tries to alter the formula, however something goes wrong and the formula makes Wayne act like a bad person. Now it is up to the rest of the family to find a way to get Wayne back. Meanwhile, Diane and Nick try to give Quark a bath.

Jennings romantically pursues Diane after using Wayne's "Electric Chair of Love"; Amy and Nick contract chicken pox, forcing Diane to move into a hotel. Only one things for sure: this ain't going to end well for Jennings.

Diane is suffering a mid-life crisis in which she tries to look younger and after a trip to the museum with her husband and son, she finds out about a spell that could make her younger. Diane translate the tablets against Wayne's wishes and unknowingly wakes up as an evil princess. Now it is up to the Szalinski team to fight the evil princess and get Diane back. Meanwhile, the chief tries to beat Wayne in a spring decoration contest.

Amy's use of a mental enhancer inadvertently gives her the power to control nature, which goes to her head as she establishes herself as a supreme ruler. Here we go again!

Amy and Nick are kidnapped by a cyborg from the future, a result of Jennings' misuse of Wayne's environment-friendly car.

Wayne works on a superhero suit to combat a crime wave by off-road bikers. Will this invention work, or will it backfire like usual?

To save his bankrupt company, Jennings sends Wayne to find a magical stone that can turn metal into gold. But Jennings' greed alters the stone's power.

Nick is running from a bunch of bullies when he takes a hard fall and a circus takes him home. The head guy steals everything in Wayne's lab so now the family must rescue Nick and they must do this by joining the circus themselves.

Nick invents a machine of his own in an attempt to resurrect his dead pet bunny, Copernicus. Things go wrong when his invention summons a monstrous creature from another dimension that possesses the body of his deceased friend.

After wrestlers Bret and Owen Hart are injured at the Szalinskis', Wayne and the Chief agree to take their places in a match, aided by Wayne's remote-controlled bodysuit.

Wayne and his family are going camping with the chief and his kids. Wayne makes a home away from home that he carries on his back. At night time during a storm it takes them back to the prehistoric age and now they must figure out a way to get back to the future.

He's invented a machine that will make old people feel and act younger. However, it takes Diane and Wayne's youth, giving it to an older couple; the effects take a long time to kick in. As the other couple grows young and immature, Wayne and Diane grow old and scared for their lives. Can Nick and Amy find the old couple and bring them back before Wayne dies of old age and can't reverse the process?

Nick is upset because he is having trouble playing baseball so he asks his dad to make some inventions to help him play baseball better. Elsewhere, Diane is worried her recital and Amy uses a cream that camouflage pimples but she uses too much and it hides her nose.

Wayne creates the Szalinski Scan-O-Caster a machine that scans text, converts the narrative into tangible holograms, and projects the stories as 3-D images. Accidentally a book falls on the machine, turns it on and makes all the Urban legends come to life. Meanwhile there's a new kid at Nick's school, David Foaf...

Wayne sees a meteorite heading for earth though his super scope. Whilst the people in town cause havoc and the people at Jentech are acting crazy, Wayne must figure out how to stop the asteroids. Things get a little more complicated when Jenning's brother has a launch system to blow up the meteorite while Wayne finds out there is life on the asteroid. Can he save the world?

Wayne creates a skin lotion to make people become great swimmers like fish in the water. Amy takes some of it to a pool party that she is invited to. When Amy uses the lotion, she becomes the life of the pool party so the girl who the party is being held for tries it as well. However, things go terribly wrong (as usual) when the girls find the lotion has turned them into "mermaids". They'll end up completely turning into fish unless Wayne can create an antidote. However, things get even worse when the desperate and greedy owner of the pool kidnaps the girls to use them as a money-making attraction.

Wayne invents a way to make veggies bigger, only it turns the veggies into big bad mutants. Quark eats some of the stuff after the Szalinskis killed the Mutant Veggies. So now Quark is mutating and looks like Godzilla! Can the family get Quark back to normal before he destroys the town?