An in-depth look at Cheng Chui Ping, who was involved in human trafficking for over 20 years.

A look at one of the few women to rise up the ranks of the dangerous Cali Cartel, Mery Valencia.

An in-depth look at the leader of a sex trafficking enterprise, Rances Ulices Amaya.

In 1986 Detroit, Demetrius Holloway rose to become one of Detroit's most notorious drug kingpins.

Albanian immigrant Alex Rudaj muscles in on Italian Mafia territory.

The patriarchs of the Black Mafia Family controlled one of the largest cocaine distribution gangs.

Ludwig Tarzan Fainberg was a middleman between the Russian Mafia and the Medellín Cartel.

How James Spencer Springette went from selling juice to tourists to distributing thousands of kilos of cocaine and being on the FBI's top ten list of most wanted.

Dustin Honken was a mastermind chemist who made and sold a deadly concoction of crystal methamphetamine, but the federal government would accuse him of much more than that when two of the key witnesses in the case against him suddenly disappeared.

Juan Ramon Matta-Ballesteros became one of the most powerful drug lords south of the border.