When Guy continues to clash with Zosia he accepts their relationship is purely professional but is that what she really wants? Meanwhile on AAU both Serena and Mary-Claire face the difficult task of picking themselves up after being fooled by Edward.

There is shock on Keller when doctor Dominic Copeland returns to Holby to retake his first year. Will Arthur forgive him for what he did to Malick? Mo's sister Adele joins AAU as the new healthcare assisstant but will there be trouble between them? Meanwhile Colette discovers Guy cut corners to give her the nursing job and now she must prove herself to somebody from HR.