Hanssen tries to bury himself in his work, but when Gaskell makes a move he hadn't bargained for, he can no longer ignore his conscience. Fletch is burning the candle at both ends, leaving Evie picking up the slack. Desperate to make things right with his daughter, Fletch faces a tough decision. Feeling more isolated than ever, Meena turns to an old flame for comfort.

In America, in 1987, three young Holby familiars make a pact to push the boundaries of medicine no matter the cost. With the life of a friend hanging in the balance, Gaskell must question his unshakeable belief in Project Laszlo.