Frieda is back and taking no prisoners. Tensions run high when Jac puts her to the test, is Darwin big enough for the both of them? Roxanna makes a devastating discovery… but will it be enough to persuade Gaskell to see sense?

Meena finds herself friendless and in need of help, how much can one junior doctor take?

A distraught Hanssen holds vigil at the hospital, while Gaskell agonises over his actions. Fletch is missing Evie and angrily blames Steven for pulling his family apart. Sacha makes a tentative return to Holby after time off for his depression.