Ange plans to tell Chloe her biggest secret, but a surprise locum throws her day into disarray. Ric's granddaughter, Darla, arrives at Holby, forcing Ric to deal with her pregnancy head on. Kian rallies Nicky and Cameron to help him find out who Jac's mystery patient is.

Dominic faces his difficult past when he goes head to head with his abusive ex, Isaac, while Ange and Carole band together to try to help him.