The 51st Annual American Music Awards were held on May 26, 2025, at the Fontainebleau Las Vegas in Las Vegas. This was the first award ceremony to be broadcast on CBS, and stream on Paramount+. Jennifer Lopez hosted the show for the second time, following the 2015 ceremony.

Nominations were announced on April 2025; Kendrick Lamar led with ten. Janet Jackson was honored with the Icon Award, Rod Stewart with the Lifetime Achievement Award, and Zac Brown with the inaugural Veterans Voice Award.

Winners: Billie Eilish, Gracie Abrams, Lady Gaga, Bruno Mars, Doechii, Post Malone, Beyoncé, Dan + Shay, Eminem, Megan Thee Stallion, Kendrick Lamar, The Weeknd, SZA, Bad Bunny, Becky G, Julión Álvarez, Shakira, Twenty One Pilots, Linkin Park, Tyla, RM.