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Cesare is brought to La Mancha and goes on trial before the Inquisition, while Lucrezia must use extreme measures to save her marriage.
Cesare stands trial for treason against the Holy See and the Ten Commandments, with his old friend Niccolo Machiavelli as prosecutor.
Cesare's ultimate judgment is realized while Lucrezia struggles to make sense of her family's history and its future.