Missy's first heartbreak triggers a series of events that lead the Cooper family to the brink.

The Coopers discuss the possibilities of black holes and alternate universes when Dr. Sturgis comes over for dinner,

Sheldon finds himself at odds with Paige once again when she considers enrolling at East Texas Tech. Also, Mary seeks June's advice when looking for a change.

Sheldon is caught in a moral dilemma when offered a bootleg copy of a computer game he can't afford. Also, Mary and Meemaw take Brenda out for girls' night while George Sr. and the guys watch Billy, and Missy asks Georgie to take her and Marcus on a secret date.

When the IRS accuses Sheldon of making a mistake, he'll stop at nothing to prove them wrong. Also, Dale is forced to get a colonoscopy and tries to convince Meemaw to join him.

Sheldon refuses to ride in a car after getting into an accident with Meemaw. Also, Missy uses their trauma to her advantage at school and Meemaw is forced to take the church shuttle while her car is in the shop.

Sheldon, Dr. Linkletter and Meemaw team up on a science experiment. Also, Mary is jealous that Pastor Jeff and Brenda are spending time together, and Georgie has a new side hustle. 

Dr. Linkletter pushes Sheldon to make friends with his fellow students at college. Also, Georgie gets a pager.

Sheldon campaigns to become Dr. Linkletter's lab assistant. Also, Georgie enlists the help of Mr. Lundy, the drama teacher, for a surprising business venture.

Sheldon and George Sr. dine with President Hagemeyer and a university benefactor. Also, Georgie gives Missy some brotherly advice when Mary won't let her go to the school dance, and Dale and June convince Meemaw to attend their son's wedding.

Meemaw takes matters into her own hands when Sheldon's philosophy teacher, Professor Ericson, sends him into a tailspin. Also, George Sr. learns Georgie has been cutting class.

Sheldon's first day of college is derailed by his new philosophy teacher, Professor Ericson. Also, Mary and Brenda live vicariously through Missy's first day of middle school.

College orientation does not go as Sheldon planned. Also, Mary is invited to a party when she's mistaken for a university student, and George Sr. helps Pastor Jeff set up a children's nursery.

Dale and Meemaw work out relationship issues while playing Dungeons and Dragons with Sheldon and Missy. Also, Mary and George take a trip with Coach Wilkins and his wife, and Georgie freaks out when his girlfriend thinks she's pregnant.

Sheldon finds himself in a fierce competition with Paige when their mothers force them to attend Vacation Bible School. George is furious after Georgie makes a questionable purchase.

With college in sight, Sheldon is determined to ride his bike without training wheels. Also, Mary and George Sr. argue over parenting styles.

Sheldon gets a summer job at the local train museum. Also, George and Missy bond when Missy embarks on a new stage of womanhood, and Georgie discovers Mary's guilty pleasure.

After graduating high school, Sheldon has a breakdown when he realizes he may not be ready for college. Also, Dale tries to make amends with Meemaw.