David goes sponge diving off the coast of Florida and visits NASA's Office of Planetary Protection in order to learn the most efficient and effective way to wash dishes.

David meets with scientists, chefs and other experts in an attempt to create the perfect slice of toast for comic Paul F. Tompkins.

David explores the science of sleep in an attempt to re-create the best nap he's ever had; humorist John Hodgman helps David appreciate the benefits of a midday snooze.

David's attempts to improve his personal signature take him from the New York Public Library to a meeting with comic Paul F. Tompkins.

David collects information from a professional cricket player, a billiards shark and two physics professors in order to learn how to properly bounce a ball.

David studies how to throw a punch and avoid being hit, and learns what happens when a punch connects; boxing champion Bernard Hopkins is recruited to deliver David's first real blow.

David attempts to eavesdrop on his friends and old bosses after learning about inconspicuous listening techniques and receiving pointers from a former CIA operative.

David attempts to determine the proper technique for petting a dog, but has to turn to actress Amy Sedaris and astronaut Chris Hadfield for help in overcoming his fear of the animal.