Nikki heads to Las Vegas to make an attempt at spending 24 hours in a strip club; Jim Norton and Bridget Everett join Nikki for a round of Tinder Tapout.

Nikki tours a new museum dedicated to relationships gone bad with Rachel Feinstein; Margaret Cho and Kurt Braunohler discuss common sexual stereotypes.

Couples that are considering a prenuptial agreement; an installment of ``Comedians Do Porn''.

Nikki delves into the topic of the popularity of over-the-counter male enhancement pills with Dr. Drew Pinsky; helps unmarried couples write their prenups.

Nikki discusses dates gone wrong with Dave Waite; plays Tinder Tapout with Ron Funches and Katie Nolan.

Nikki teams up with a group of women to conduct research on the female orgasm and learns about flirting.

Nikki attends a Donald Trump rally in San Diego to see what his supporters think about sex; explores what constitutes cheating.

Nikki enlists musician Omarion to create a new R&B hit based on real-life sex stories and then plays another round of What's Your Number? with Anthony Jeselnik and Riki Lindhome.

Nikki uses the magic of porn to discuss women in the workplace with Kristen Schaal, then chats with guests Chris D'Elia and Kate Walsh.

Nikki takes a look at the world of professional cuddlers and plays a round of Tinder Tapout with special guests Mary Lynn Rajskub and Adam Pally.

Nikki explores the world of pegging and plays a round of Tinder Tapout with special guests Patton Oswalt and Natasha Leggero.

Dan Savage gives advice to Nikki's younger self, Todd Glass debunks gay stereotypes, and Nikki interviews a man who loves to sniff women's underwear.

Nikki presents a PSA for guys who have one-night stands and plays "What's Your Number?" with guests Kyle Kinane and Kristen Schaal.

Moshe Kasher and Grace Helbig share items from their sexual bucket lists, engaged couples apologize to their friends, and Nikki rails against bikinis.

Nikki takes on the subject of polyamory, interviews an Uber driver about a hookup with a passenger and chats with T.J. Miller and Pete Holmes.

Nikki talks to hotel maids to hear horror stories about cleaning up after guests have sex; plays a game of Tinder Tapout; and talks to people about digital penetration.

Nikki sits on a sex toy and discusses female ejaculation with Sara Schaefer; she researches her parents' sex lives.

Nicki helps porn actors with their lines; and talks about friends who've been left behind with Chris D'Elia and Esther Povitsky.

Nikki stages a photo shoot to help men work on their sexting skills; and picks up guys coming out of strip clubs to quiz them on women.

Rory Scovel and Rachel Feinstein join Nikki to see how much a guy will put up with on Tinder; Nikki dives into the topic of the friend zone and attends a foot fetish party.