Samantha Janus guest stars as the wife of a man with a muscle-wasting disease, who arouses Kim's suspicions when she comes into the hospital sporting bruises. Danny struggles to cope with Cady, while Harding and David are unsure what to tell Anna about the factory's problems. Nathan worries about Billy's parenting skills, and Zoe gets more than she bargained for after organising a pub quiz team.

Jack Clayton (ex-Emmerdale actor Ian Kelsey) and his family visit Skelthwaite, the home town of his wife Nisha (former Coronation Street actress Shobna Gulati), who happens to be a nurse - handy for Anna, who is struggling to replace Kim. David doesn't feel like celebrating his birthday as the factory's problems reach crisis point, and Zoe becomes suspicious of a patient's boyfriend.