Skelthwaite is buzzing on Luke and Megan's wedding day, but there's more in store for the guests than many anticipated. Billy shares an unexpected kiss with single mum Terri, while Danny struggles to say the right thing to Zoe. Anna tries to share Harding's enthusiasm for the relaunch of Goddard's, and disaster strikes for two passengers on the way to the ceremony.

Weighed down by the pressure of her fight against Greenwoods and Luke's wedding, Anna is forced to consider accepting Robert Ashford's offer for the land. The men at Goddard's are confused when a lorryload of pulp paper arrives out of the blue, while Zoe attempts to persuade a local butcher he is working too hard to keep his shop afloat.

Anna organises a picket of the Greenwoods site, but faces opposition to her protest from the police, while Harding considers a tempting business offer. Alfie Gough's health starts to deteriorate, and Nisha uses all her resources to help a patient whose boyfriend is in a coma - leaving her oblivious of daughter Rowan's increasing closeness to Robert Ashford.

Nisha's first week as a Skelthwaite nurse begins badly when she clashes with Anna over the treatment of a dying patient. Danny struggles to combine his new job as a barman with taking care of Cady, while a campaign against Greenwood's supermarket begins. The rugby team are feeling disheartened and in need of help - but Jack Clayton might be just what they're looking for.

Jack Clayton (ex-Emmerdale actor Ian Kelsey) and his family visit Skelthwaite, the home town of his wife Nisha (former Coronation Street actress Shobna Gulati), who happens to be a nurse - handy for Anna, who is struggling to replace Kim. David doesn't feel like celebrating his birthday as the factory's problems reach crisis point, and Zoe becomes suspicious of a patient's boyfriend.

David and Anna's plans for a romantic weekend away are shattered when their family and friends decide to join them, and Luke has an important question for Megan. Meanwhile, Billy faces up to Sally's death and Zoe crosses swords with feisty local Gaynor, who is intent on cleaning up the canal.

Samantha Janus guest stars as the wife of a man with a muscle-wasting disease, who arouses Kim's suspicions when she comes into the hospital sporting bruises. Danny struggles to cope with Cady, while Harding and David are unsure what to tell Anna about the factory's problems. Nathan worries about Billy's parenting skills, and Zoe gets more than she bargained for after organising a pub quiz team.

Matthew Kelly guest stars as factory worker Barry, whose shocking secret is revealed when Zoe goes to give a healthy eating talk at his firm. The trainee nurse also finds romance with a sexy stranger, while Harding is concerned about the arrival of an old rival in Skelthwaite. The rugby pitch gets waterlogged - so Billy persuades his team-mates to try cookery classes.

Skelthwaite struggles to adjust to the loss of Sally Boothe, as husband Billy vows revenge for a rugby team's prank rather than face the reality of his wife's death. Anna and Kim welcome the latest recruit, excitable trainee Zoe Phelps, while the hospital staff attempt to make a young heart transplant patient's wish come true