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Surgeons attempt a rare and high-risk transplant to transform their 21-year-old patient's life and perform a complex kidney procedure vital for another patient's survival.
Surgeons battle to save a patient with an aggressive tumour and a patient whose aorta – the body's biggest artery – could rupture at any moment.
The new series will be filmed in Edinburgh and The Lothians at some of the region's leading centres of medical excellence - NHS Lothian's The Royal Infirmary, Western General and St. Johns.
With unprecedented access to surgeons, anaesthetists, theatre staff and patients, the series will once again offer a unique insight into to the innovative and experimental surgeries taking place on the frontline of medical science.