The year is 2031 and following the defeat of the Robotech Masters by Earth's Robotech Force headed by Dana Sterling's 15th Tactical squad, the planet faces a new threat! The spread of the Protoculture spores across vast swathes of the Earth's surface has not gone unnoticed. The mysterious alien race known as the Invid - arch enemies of the Robotech Masters - launch a full scale invasion of Earth. The remaining inhabitants of the planet must struggle to survive against the new alien threat. With only a rag-tag collection of guerilla fighters to defend them, the survivors can only pray for the return of the long forgotten Robotech Expeditionary Force (REF) to save them from total annihilation.

Fifteen years have passed since the war against the Zentraedi Forces.

The peaceful life of the survivors of the first alien battle ends with the invasion of the Robotech Masters. They have come to Earth to reclaim the Protoculture Matrix, the power source for the mysterious Robotechnology that was discovered by mankind decades earlier when the interstellar batter-cruiser, the SDF-1 crash landed on Macross Island

Ten years of furious conflict and frenzied construction have turned an alien wreck into human triumph; the colossal space battleship Macross. On the day of the ship's launch, a world waits with bated breath to witness mankind's next giant leap.

Hovering above the planet, though, the Zentradi, a merciless warrior race, seek to advance their agenda of destruction and conquest. When long-dormant systems aboard the Macross suddenly fire upon the alien fleet, the ship meant to preserve humanity may become its undoing. A war of attrition erupts, taking mankind across the solar system and beyond in a fight to justify its existence