Audrey has a severe condition that leaves her with painful bumps on every inch of her body. An embarrassing armpit growth affects former marine Matt's self-esteem. Jaclyn has a lemon-sized bump on the back of her head.

Shakisaha's earlobe split in half during a failed body modification attempt. After recovering from a flesh-eating disease, Kelly Ann developed a huge leg growth. Terrified of doctors, Dennis has gone 30 years without seeking treatment for his head bumps!