A Boer goat has lost 50 pounds after refusing to eat. While examining the goat, Dr. Pol assumes the goat must have some sort of parasite. He confirms it is Coccidia–-a dangerous, one single-cell parasite that infects the intestinal tracts of animals.

Dr. Pol's next farm call requires him to take blood samples from a flock of sheep in order to test for OPP – Ovine Progressive Pneumonia, a progressive disease that is incurable and highly contagious. But it's not as easy as it sounds, Dr. Pol and Charles will have to wrestle the sheep before they can get the samples.

In another emergency farm call, Dr. Pol must treat a dairy cow with a Left Displaced Abomasum, or a twisted stomach which means that one of the cow's four stomachs has floated to the top of the abdominal cavity. Dr. Pol will have to perform a procedure to suture that stomach to the wall of the cow's belly.

Dr. Pol receives an emergency call from a client who finds her horse down and fears he may not make it. Suffering from a spinal cord injury, he decides to give the horse a cortisone shot. Will he survive? Dr. Pol's son, Charles decides to extend his visit to help his father with the work overload. His only request—to palpate a cow. But trouble creeps up when Dr. Pol and Charles perform an emergency futotomy, an intense procedure to extract two dead fetuses from a cow.