The vets have their hands full with a motley crew of pups.

Pol Veterinary Services receives a call about a rescued Saint Bernard in a life-threatening situation. Left outside in the blazing summer sun, this abused dog needs Dr. Pol's help recovering from potential heatstroke. Dr. Pol and Diane care for the Saint Bernard and nurse him back to health. Eventually, they fall for the loveable lump and are determined to keep him out of the pound and in a suitable home.

Over the years, we've seen world-famous veterinarian Dr. Pol wrangling animals, tackling cases and dealing with some wild situations. Now, take a trip with us down memory lane as we look back at some of the show's most incredible moments, remarkable cases and favorite memories over the past 100 episodes.

Weird things happen every day at Pol Veterinary Services, but things are downright strange this week as Dr. Pol and his team treat some of the most bizarre patients they have ever seen. Their cases include a red-necked wallaby with a peculiar protrusion, a cow with a mutant baby, and an extra tiny two-pound goat.

Pol Veterinary deal with neck bites and thunderous growls during the Halloween season.

As late spring turns to summer, one thing remains constant at Pol Veterinary Services - the vets are busy with patients in need. Dr. Pol, Dr. Brenda and Dr. Emily shift into overdrive to meet the needs of their clients, until some extra help arrives. The Pol Clinic veterans take a new vet, Dr. Erin, under their wing, as they flip cows, clamp calves, tube horses, and treat a rescue rooster.

The Pols find time away from a wide array of clients to work on their lake house.

In case of emergency, dial Dr. Pol! The stakes are high for Dr. Pol and the clinic staff as animals across central Michigan find themselves in one complication after the next. Dr. Emily rushes to treat a dog that had been shot, and then responds to another call involving an injured Beagle. Meanwhile, Dr. Pol and Charles get roped into an unexpected rodeo that puts Charles out of commission.

Another not so average week for Dr. Pol and his team.

This spring, the Pols are filled with excitement as they attend to a very special pet project: their Friesian horse, Anneke, is expecting! After 11 long months, Anneke finally gives birth to an itty bitty stud colt. Dr. Pol and Diane adore their new baby but are deeply concerned about his size ... he's lighter than expected. They pull out all the stops and to nurse their new baby to health.

The first days of autumn bring beautiful color to the Michigan countryside and a new vet to Pol Veterinary Services.

It's another wild week in Michigan. From animal attacks to breakaway bovines to slick sheep, the team at Pol Veterinary Services is busy on call as the cases keep rolling in. Meanwhile, Charles has his plate full with a plan to go green at the clinic and at home. He's leading the charge to help the Pols get eco-friendly for a sustainable future.

The first days of autumn brings a new vet to Pol Veterinary Services.

The clinic is going to the dogs as the vets have their paws full with this motley crew of pups. From limping labs and damaged danes to Pomeranian's with pimples and terriers with tooth trouble, the clinic is busy helping man's best friend.

Spontaneous blizzards and chill temperatures are complicating things at Pol Veterinary Services this spring, but that doesn't slow the team down. A late-night emergency keeps Dr. Pol at the clinic during a snowstorm while Diane copes with a power outage. The weather interruptions continue as Dr. Pol is called out to treat a first for him: a wild Sandhill Crane with life-threatening injuries.

The team celebrates all the mothers.

Pol Veterinary Services has an exciting new addition to the clinic staff: Dr. Emily's husband, Tony! The team is grateful for the extra help as they receive a slew of difficult cases. A complicated calving in dangerous weather conditions, a dog with "swimmer puppy" syndrome, and a cow with a cut milk vein have the team running on all cylinders.

Everyone gathers to welcome the newest member of the Pol Veterinary Services family.

Neither rain nor snow can stand in the way of the team at the clinic. But this year, the weather is putting them to the test! Meanwhile, the veterinarians respond to an array of wild cases, including a huge, rambunctious boar with razor-sharp tusks, a near-fatal skunk attack, and a twisted uterus. Then, Michigan mud season kicks in and it seems nothing is working in the vets favor.

Dr. Pol is partially colorblind, so when Charles hears of a new technological breakthrough, he decides it's time to give his dad the greatest gift of all - the gift of color.

Broken toes, worm infestations, and nursing puppies send the clinic into a whirlwind. Dr. Pol and Diane are short-handed and Charles goes out of town at the last minute, so the Pols call in some backup. Dr. Pol and Diane's grandchildren, Adam and Rachel, hurry to help out. Stakes are high Dr. Emily performs two lifesaving surgeries on one of the worst cases she's ever seen!

The Pol team deal with llamas, a surly highlander and other surprises.

Ho, oh, no! It is the holiday season in Michigan and Dr. Pol and his team make their patient list, check it twice, and treat those who are naughty, spotty, snotty, and nice! The clinic meets with a dog owner who suspects her dog ate Christmas lights and Dr. Pol rushes the young pup in for an emergency x-ray. Meanwhile, Dr. Emily rushes to help a calf with an enormous amount of fluid in its lungs.

Pol Veterinary handles cases from colorful parrots to a sick zebra while celebrating Dr. Pol's birthday.