When their building is infested with bed bugs, Mulaney and the gang secretly crash at a Lou's vacant pad and unknowingly eat some special Oscar "treats," leading to more problems when Lou unexpectedly returns from vacation early.

John puts his theories about teenagers to the test when he tries to impart his wisdom to his new girlfriend's 13-year-old daughter. Meanwhile, Jane and Motif become Lou's lunch companions.

John takes Lou's advice about how to gain the upper hand with his roommates. Meanwhile, Motif shows Jane how to get her new cat to like her.

John faces the dilemma of being mean about Lou when he is invited to participate in a celebrity roast. Meanwhile, Oscar teaches Jane how to be more ladylike.

John quickly regrets mixing his home and work lives when Jane becomes Lou's new personal trainer. Meanwhile, Motif turns to Oscar for advice on his stand-up routine.

John's resentment of actor Macaulay Culkin dampens his Christmas spirit. Meanwhile, Lou is worried when his rival, network host Jesse Tyler Munoz (guest star Kroll), announces a competing holiday special, and Andre is mistaken for a puppet.

Motif gets "Carrie'd" away and relies on his three girlfriends for support when he learns that John and Jane will not add him to the apartment lease. Meanwhile Lou's audience plant demands a contract.

When Jane starts dating a marine, John and Motif, feeling guilty for their lack of service, try to sign up for a USO Comedy Tour. Meanwhile, Lou recounts how war - and improv - are hell.

John's very Catholic parents pay him a visit, which means it's time to start lying about being a devout churchgoer. Meanwhile, Jane decides to go on "the pill" and must suffer the side effects, all to impress a guy.

Mulaney tries to figure out why Jane doesn't like any of the girls he dates. Meanwhile, Lou fixates on the idea of his death, and asks John for help in planning a dignified demise.

As a tribute to his deceased neighbor, Lapidus, John uses his jokes for Lou's monologue. Then, in an effort to please Lou and make sure his contract, which expires on Halloween, is renewed, John stops at nothing - including potential grave robbery - to retrieve more of Lapidus' material and prove his worth to Lou.

John learns to face his fear of childbirth when he starts dating a doula. Meanwhile, at work, he is tasked with confronting Lou about his provocative on-camera behavior.

In the Series Premiere, JOHN gets a job writing comedy for demanding and infantile game show host LOU CANNON, which turns out to be less glamourous than expected. Meanwhile John's roommate, JANE, attempts to prove to an ex that she isn't "psycho"; and his other roommate, MOTIF, struggles to write a joke with a killer punchline.