The story starts with a murder in Whitechapel. Four different detectives are trying to solve the murder in different time periods: 1890s overachiever Edmond Hillinghead, dashing 1940s adventurer Karl Whiteman, kickass female 2010s Detective Sergeant Shahara Hasan and Maplewood, an amnesiac from post-apocalyptic 2050, who brings a haunting perspective. Together, the four set out to uncover a conspiracy spanning 150 years.