In Harris County, Deputy Jason Brown is called out on Easter Sunday to investigate the brutal shooting of a woman who was a school bus driver and mother of two. Meanwhile, Harris County Sergeant Sidney Miller takes on the murder of a young father, shot dead in a courtyard.

When a 16-year-old boy is murdered at his family's roadside taco stand, Harris County investigator Sergeant Henry Palacios is faced with one of the most tragic cases he has ever seen. Palacios is hot on the trail of his suspect, when another shooting turns the case on its head.

In Miami, Detective Anthony Reyes and the homicide team are investigating the murder of a middle-aged mother of four, shot to death in a random robbery outside a public storage facility. With no witnesses to the actual shooting, detectives must rely on surveillance footage, which could be the key to solving their case.

In Birmingham, Det. Jerry Williams and his team investigate the murder of a young man shot dead in an abandoned apartment. With little physical evidence, Williams must rely on witnesses to help him piece together the puzzle and find the killer. In Louisville, Det. Brenda Wescott investigates the unusual death of a woman shot dead on a residential street.

In Louisville Kentucky, rookie detective Holly Rogers is called to the scene of a convenience store robbery that left a 30-year-old employee in critical condition. With strong photographic evidence from security cameras and a trail of physical evidence to follow, Rogers and her team race against the clock to identify and apprehend the shooter.

In Miami Sgt. Altarr Williams and detective Frankie Sanchez investigate the murder of Darrell Harrell, gunned down for trying to push a group of drug dealers out of Overtown. Months pass without a lead as the team tries everything they can to keep the case from going cold.

In Harris County, Dep. Mario Quintanilla investigates the murder of a woman shot during a robbery of her illegal game room. Acting on a tip that his suspects are from Central America, Quintanilla races to find them before they can flee the country.

In Louisville, Det. Brenda Wescott and partner Det. Collin King are hoping to solve the murder of a man whose identity is a mystery. After following all her leads to dead ends, Wescott is afraid the case will go unsolved--but then things takes an unexpected turn. In Birmingham, Det. Jerry Williams and his team are trying to piece together what happened to two men found dead in a strange house.

In Birmingham, Detectives Mike Allison and Cynthia Morrow investigate the tragic case of a mother shot in her car while her three young children sat in the back seat. As detectives close in on a suspect, they are stunned to learn what triggered the shooting.

When a twenty-nine-year-old man and his paralyzed mother are shot to death in their apartment, Louisville detective Kyle Willett is called to the west side of town to lead the case. As the investigation unfolds, Willett and his team are shocked to learn what initiated the double homicide - a schoolyard fight between two teenaged classmates.

In Birmingham, Det. Eric Torrence investigates the death of a 24-year-old father-of-two shot in the street. 36 hours later Det. Cynthia Morrow is called out to the murder of a 27-year-old man found in an open field. While Torrence struggles to find anyone who will ID his suspects, Morrow runs into similar problems trying to locate the last person seen with her victim.

In Birmingham Det. Cynthia Morrow and the homicide team try to weave together the events of drug deal gone bad when two brothers from out of town get more than they bargained for. In Louisville Det. Kristen Downs leads the investigation of a possible gang-related shooting. But when no one is willing to talk, the team is forced to turn to forensic evidence to piece together the murder.

In Cincinnati, Detectives Matt Thompson and Doug Lindle are investigating the double homicide of a local hairdresser and his elderly neighbor, both stabbed to death and set on fire. When detectives discover that one of the victim's cars is missing, they begin following a twisted trail of clues they hope will lead to the killer.

In Harris County, Sgt. Craig Clopton and his team investigate the murder of man killed by a single gunshot while being robbed. With little evidence on the scene, they must rely on an eyewitness to help them identify their suspects.

In Louisville, Det. Carl Payne and the homicide team investigate the murder of a young man shot to death in the middle of the street in broad daylight. When a witness leads Payne to a suspect with one eye, he is surprised to learn what may have triggered the homicide.

In Louisville, a murder hits close to home when Detective Rick Arnold learns that the victim of his most recent homicide case is the brother of a good friend. If Arnold is to track down the suspect, he needs to discern between lies and truth--and real names and aliases. In Harris County, a popular teenager is gunned down on a residential street.

In Harris County, a family is devastated when their teenaged son is shot and killed after a confrontation outside of a high school party. After interviewing the party patrons, Sgt. Wayne Kuhlman and his team learn that the victim may have been mistaken for a local gang member based on the color of an item of clothing he was wearing.

In Louisville, Det. Corey Cadwell and his team investigate the murder of a 28-year-old father stabbed to death while working his shift in a smoke shop. Detectives cross the Kentucky state border into Tennessee in search of three potential suspects who mysteriously fled just after the murder.