In Cincinnati, Detectives Jenny Luke & Bob Randolph find a young woman who has been strangled in her living room. Crime scene evidence leads detectives to believe she may have known her killer. In Miami, a 65-year-old man is found dead in a pool of blood.

In Texas a young man is set up for a robbery when he answers an ad for a car in a town a hundred miles from his home. He is carrying cash and the supposed buyer demands the money. Police have a witness but her description isn't going to be definitive. In Miami a man who owns a small business is shot multiple times and robbed. The early investigation finds that the man had a proclivity for dating every woman he could and keeping pictures and clothing from those contacts. Detectives start their investigation with the assumption this is a revenge killing.

In Dallas, Detective Phil Harding investigates a brutal shooting in a motel parking lot that killed a 22-year-old and injured two of his friends. The surviving victims are the only ones who can identify the suspects. Detectives just have to convince them to talk. Then, in Memphis, Sergeants Ron Collins and Kevin Lundy must track down a murder suspect who may have fled the state.

In Miami, Detective Rolly Garcia investigates the murder of a 17-year-old boy beaten to death and dumped in the back seat of his car. To find his suspect, Garcia must first track down the victim's secret girlfriend, who may have been the last person to see the victim alive. And in Dallas, a young man is found shot dead in the parking lot of a housing complex.

In Miami, Detective Ricardo John is investigating the brutal homicide of a 19-year old girl. The detectives believe that she may have been murdered to send a message to her boyfriend, an alleged drug dealer.

In Miami, FL, Detective Freddy Ponce and Sgt. Louis Melancon unravel the mystery of a man found shot dead in his car. The key to the case could be the victim's cell phone, which was stolen shortly after the murder. In Memphis, TN, Sgts. Caroline Mason, Tony Mullins and JT Max investigate the murder of a man found shot dead in a backyard.

In Detroit, Officer Anthony Wright Jr. is investigating the death of a man found shot behind an abandoned house. Wright learns that there has been a second shooting just minutes after the homicide, and it has been caught on tape. In Memphis, when a woman is found dead inside a house fire, Sergeant Kevin Lundy, who spent over a year working in arson, is called to the scene.

In Miami, Detective Ricardo John discovers a man stabbed to death behind an abandoned church. With no identification, the investigation hinges on identifying the victim through his fingerprints. When John finally gets a name for his victim, he is running out of time.

In Detroit an young man with a new job is playing basketball in the neighborhood he hangs out in when he gets into a fight with some young men who hang out in a house right across the street from the court. The dead man breaks away from the fight and runs up on a porch and in tussle he's shot in the head. In another case a young man is shot outside a club in Dallas. The victim was apparently helping another man who was being robbed when he was shot. There are lots of witnesses but no one will talk. They all afraid to cooperate.

On a rainy night in Detroit, Sgt. Mike Martel finds a young man shot to death in a neighborhood yard. Martel finds he must rely on a friend of the victim's to help him close the case. And in Miami, Detectives Castillo and Castellanos work the murder of a young man brutally shot in broad daylight.

In Miami, Det. Armando Aguilar may be working his last case in homicide. He must unravel the sad and mysterious death of a 14-year-old boy found decomposing in a dumpster. In Dallas, Det. Randy Loboda investigates the stabbing death of a Honduran immigrant found in an alley. The suspect goes on the run, and Loboda needs to bring him in before he can flee the country.

In Dallas, Det. Dan Lusty and the homicide squad find a man with his throat slashed floating in a creek. The mystery deepens when they dig deeper into the victim's personal life. And in Memphis, Sgt. Kevin Lundy and his team investigate the murder of a 19-year-old man gunned down in the middle of a street. They soon find a witness whose story turns the investigation on its head.

In Dallas, Det. Dan Lusty and the homicide squad find a man with his throat slashed floating in a creek. The mystery deepens when they dig deeper into the victim's personal life. And in Memphis, Sgt. Kevin Lundy and his team investigate the murder of a 19-year-old man gunned down in the middle of a street. They soon find a witness whose story turns the investigation on its head.

In Cincinnati, a well-loved 58 year-old man is found shot dead in a hallway, still clutching a five-dollar bill. Detectives Matt Thompson and Doug Lindle visit the grief-stricken wife and learn the victim was murdered a day before his birthday. Thompson and Lindle rely on the help of the community to track down the suspects last seen with the victim moments before he was murdered.

In Miami, a recent high-school graduate is gunned down and left to die in his father's arms. It's up to Sgt. Eunice Cooper and her team to track down the suspects, two teens who fled the scene on bicycles. And in Cincinnati, Detective Jenny Luke is on the trail of a man who may have taken revenge on a childhood friend he thought snitched on him.

In Cincinnati, a teenager watching a street fight is killed by a stray bullet. With little to go on, veteran homicide Detective Bob Randolph must piece together the truth behind who pulled the trigger. In Dallas, TX Det. Rick Duggan and his team find a victim shot and left behind a vacant house. With no leads, Det. Duggan must turn to the victim's best friend for help.

In Dallas, Detective Eddie Ibarra discovers a woman shot dead in the lobby of her workplace. When he uncovers video surveillance of the murder he is given an unusual piece of evidence: an image of the killer. Ibarra takes on the difficult job of putting a name to the face.

In Miami, a man is gunned down at close range in broad daylight. Det. Freddie Ponce and his team follow a blood trail at the scene to an apartment complex, where they believe the suspect is hiding out. In Cincinnati, Dets. Doug Lindle and Matthew Thompson investigate the murder of a man shot outside his apartment.