Wishing to take over the world, Dr. Doom steals Silver Surfer's power cosmic again and becomes literally unbeatable. The Fantastic Four's figure that the only thing stopping him now is Galactus' power.

The Fantastic Four help Black Bolt save his people - the Inhumans - who live imprisoned under an unbreakable dome guarded by a simple, but relentless robotic sentry, who misunderstood his orders to protect the Inhumans forever.

Impish alien trickster dubbed the Impossible Man and Inhuman Lockjaw help the Fantastic Four fight the Super-Skrull.

The Fantastic Four stops the Skrulls once again, but Sue ends up in a coma and her dad is framed. The Skurlls also send Super-Skrull again, this time masked as Sue. Meanwhile, Skrull warlord Morrat tries to take over the Skrull empire.

Dr. Doom manipulates the unstoppable Hulk into fighting the Fantastic Four. Only the Thing's girlfriend Alicia can help.

Galactus' new slave and herald, double-crossing Terrax, asks Fantastic Four for help. However, Johnny's Inhuman girlfriend Frankie supports Galactus. Thor arrives to help the Fantastic Four and even mythical Ghost Rider intervenes.

Black Panther, the king of a secretive high-tech African tribe, challenges the Fantastic Four. Once defeated, he asks for their help to stop Ulysses Klaw, a mad scientist who killed his father and wants the tribe's powerful alien ore.

Ego, the Living Planet, a unique monster planet that devours planets just like Galactus, enters the solar system to eat Earth.

The Invisible Woman falls under the sway of the Psycho-Man, who alters his personality into the malevolent Malice, pitting her against her own family.

The Fantastic Four journey to Attilan and assist the Royal Family in restoring Black Bolt to the throne, but must contend with Black Bolt's treacherous brother Maximus and the swarms of Inhumans loyal to him.

The Human Torch pursues Medusa, only to stumble into her relatives, the Royal Family of the Inhumans. The Inhumans mistake the Fantastic Four for enemies.

The Frightful Four join forces to defeat the Fantastic Four, using the Wizard's machines to brainwash the Thing into switching sides.

The Fantastic Four lose their powers, inspiring Dr. Doom to conquer their headquarters. Daredevil comes to the team's aid.