Rob and Brenda Andrew are a devout couple, living in the Bible Belt of Oklahoma City. But their world is shattered when both of them are shot during a violent home invasion. The mastermind will prove to be closer than anyone ever imagined.

Bill and Mary Yoder are a happy couple, running a medical practice outside of Utica, New York. But their world collapses when Mary becomes mysteriously sick, and detectives prove that her illness was no accident.