As the hunting season heats up, Troy, Chase and Bill dive into deep water to catch pythons, but might be in over their heads. Meanwhile, Bruce and Zak fear they've bitten off more than they can chew when they venture into Viper Jungle, an area filled with venomous rattlesnakes and moccasins.

When Troy, Chase and Bill mount an airboat to hunt an area pythons are raiding alligator nests, an unfortunate mishap could leave them stranded overnight. Meanwhile, Bruce and Zak's journey into an abandoned ghost town with a haunted past, leads them to an unexpected opportunity.