Within the past decade, dozens of young Indigenous women and girls from the Crow and Northern Cheyenne Nations have disappeared from Montana's Big Horn County and its surrounding areas. Grieving Native families who fear the worst press local law enforcement for answers, but their pleas are most often met with silence or indifference. Arrests in these cases are rare, and convictions are virtually nonexistent. Elsewhere in America, similar stories of disappearances and death shock communities and become nationwide news, but when they occur on Native land, a circle of bereft family members, friends, and activists are left to fight for justice on their own. Murder in Big Horn intimately embeds with these families and this community in an effort to shine a light on the unanswered mysteries of this land.