The search for Scylla comes to a shocking end as Sara takes a hostage, T-Bag and Gretchen have their last stand at Gate, and Michael and Lincoln come face-to-face with the General and are betrayed by one of their own.

Michael and Lincoln race to get Scylla back from Gretchen and her new partner who are just as determined to get a missing piece of the puzzle from the brothers. Meanwhile, Mahone meets with an old colleague who is torn between friendship and duty, and T-Bag's faith is put to the test while holding Gretchen's family hostage.