House of Guinness will tell the epic story of one of Europe's most famous and enduring dynasties – The Guinness Family. Set in 19th-century Dublin and New York, the story will focus on the consequences of the death of Benjamin Guinness, the man responsible for the extraordinary success of the Guinness brewery, and the far-reaching impact of his cunning will on the fate of his four adult children, Arthur, Edward, Anne, and Ben, as well as on a group of Dublin characters who work and interact with the growing juggernaut that is Guinness.