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MacPherson engages in a scheme to secretly sell off Warehouse artifacts, leaving a trail of clues that lead Artie, Pete, and Myka directly to him.
Myka travels home to see her dying father only to discover that he's the victim of an artifact.
While Pete, Myka, and Claudia are trapped in the warehouse, Artie is forced to answer to his superiors.
While Pete and Myka investigate a series of artifact-related suicides at a Florida prison, Claudia uses an artifact at the warehouse.
Pete goes to Las Vegas with Myka to recover an artifact from a couple of gamblers... unaware that the real Myka is trapped in a mirror at the warehouse.
On the trail of a samurai sword gifted to the President, the agents encounter a rival artifact-seeker.
Pete and Myka take on a previous agent's assignment after the man's corpse turns up in the basement of a St. Louis police station.
The theft of a sculpture leads Myka and Pete to a sacred Indian cave holding an ancient secret of creation... and destruction.
A woman kidnaps Artie and insists that he help her recover her brother... who was lost in an artifact-related experiment 12 years ago.
Pete and Myka are sent to investigate a town where the inhabitants' minds are being altered making them act as they please. Meanwhile, Artie is confused by the energy flows going on in the warehouse.
Pete and Myka are after a team of bank robbers who have a distinctive weapon. Meanwhile, Artie examines the security breach at the warehouse.
Secret Service agents Lattimer and Bering are "rewarded" with a transfer to the top-secret Warehouse 13. They meet Artie Nielsen, the caretaker of the mysterious warehouse, who tells them about their new job. The agents are responsible for the collection of every supernatural and unexplained item that the U.S. Government has ever collected. For their first assignment, they are sent to Iowa to investigate a possible artifact belonging to a college student who went berserk and assaulted his girlfriend while chanting an Italian incantation.